Christina Applegate has confirmed the recent reports of her hospitalization.
The entertainer sparked concerns following reports of her hospitalization for unknown medical reasons. At the time, her rep refused to confirm or deny the speculations but cited her ongoing battle with multiple sclerosis (MS).
Christina Applegate stepped away from on-screen roles in 2021 following her diagnosis with the neurodegenerative disease. She currently co-hosts the “MeSsy” podcast with Jamie-Lynn Sigler and recently released a memoir.
Christina Applegate Reassures Fans Of Her Resilience Following Hospitalization Rumors
Applegate broke her silence on the hospitalization reports on Monday, April 20. She shared a picture of a white mug with the words “kissy kissy” and two kiss marks adorning its body. The mug sat on top of her new memoir, “You With Sad Eyes,” which rested on a wooden rail.
The picture, shared on Instagram, was taken outdoors with a green scenery in the background. The snap seemingly confirmed that Applegate was no longer at the hospital, and she further fueled this concept by raving about her resilience in the post’s caption.
“Thank you for the outpouring of love and well-wishes. Health issues are a constant for me, but I’m a strong chick, and I’m getting stronger and better every day,” Applegate wrote. She added that she was focused on her health and would share more details about what happened at a later date.
The Podcast Host Receives Love And Support From Fans
Applegate’s post received over a thousand comments from fans and other celebrities, who penned their love and support for the retired actress. “Christina, just in case today’s mail got lost: We, the public, would like to formally submit that we adore you, support you, and RIDE AT DAWN FOR YOU ALWAYS,” actor Cheyenne Jackson wrote.
Actress Olivia Munn showed her support by dropping multiple red heart emojis, with David Faustino following suit. Actress and singer Traci Lords also showcased her love with emojis, commenting three kiss emojis. Fans joined the sentiments by thanking Applegate for the health update.
“We love you, Applegate!!!!! You are strong, chica!!!” someone declared. Another agreed, labeling Applegate “a warrior.” The supportive comments continued, with fans claiming they had read Applegate’s memoir or listened to the audiobook and loved it.
The Retired Actress Was Reportedly Hospitalized For Weeks
The Blast covered the reports of Applegate’s hospitalization, sharing that sources claimed she had been admitted at a Los Angeles facility since late March. The reason behind her hospitalization was not revealed, with Applegate’s representative choosing silence.
The rep stressed that they could not confirm or deny the stories about Applegate’s hospitalization. They also refused to share any details about the current status of her health, but referenced her ongoing battle with multiple sclerosis.
“She’s had a long history of complicated medical conditions that she has been refreshingly open about,” the rep said. The news of Applegate’s hospitalization came weeks after her “MeSsy” podcast co-host, Jamie-Lynn Sigler, announced their hiatus.
The Media Personality’s Loved Ones Are Allegedly Prepared For Her Death
During the March 31 episode of the podcast, Sigler explained that she and Applegate would be taking a brief hiatus amid their respective book tours. Applegate’s memoir dropped last month, detailing her emotional battle with the neurodegenerative disease.
The disease has reportedly taken its toll on those in Applegate’s inner circle, with a source shedding light on how her recent hospitalization had impacted them. The Blast shared that the source claimed: “everyone has it in the back of their minds that they might not have a tomorrow with her.”
Another source added that Applegate had “better days and really bad days,” but “she doesn’t have great days.” They noted the retired actress was putting up a fight with the support of her loved ones, who held on to the hope that she would live longer than they feared.
Christina Applegate Got Candid About The Unflattering Side Of Her MS Battle
Applegate has been vocal about her multiple sclerosis since her 2021 diagnosis, even sharing TMI details about her health. The Blast reported in March 2025 that Applegate had opened up about the unflattering side of the neurodegenerative disease.
During the episode of her podcast, Applegate revealed that she often threw up whenever she used the restroom. She shared the details while responding to a fan who complained about having frequent diarrhea and vomiting issues amid their MS battle.
Applegate believed there was a link between stomach problems and MS despite doctors not being convinced of one. She claimed she had been admitted to the hospital for symptoms such as vomiting, diarrhea, and pain in her stomach at least 30 times.
Stay strong, Christina Applegate!