It all started Monday with the "Rebel Heart" singer taking a jab at Gaga after a video compilation circulated showing the "Star is Born" singer repeatedly saying, “There can be 100 people in a room and 99 of them don’t believe in you, but all it takes is one and it just changes your whole life” during her movie's recent press tour.
Madonna thought Gaga's quote sounded pretty familiar and shared an interview from over 30 years ago where she's quoted saying, "If there are 100 people in a room and 99 say they liked it, I only remember the one person who didn’t.”
But that wasn't enough for Madge, who also posted a photo of herself with the caption, "Don't f*^k with me Monday." That didn't sit well with Gaga's Monsters and they went into full defense mode.
"What you said decades ago was different than Gaga-and with different meaning-and you know it. She is 100 you could only ever be 99," one fan wrote on Madonna's IG. "Jealousy is not very becoming of you," said another.
And, of course, Madonna's fans fought back.
"She'll never win the crown!! It's good to be the Queen!" one fan shot off. "U re the One and Only Queen @madonna," another fan posted.
Madonna has since taken down the interview footage, but the damage was already done ... especially because the two have drama from the past.
In 2012, Madge went on record saying Gaga "references me a lot in her work" and called “Born This Way” “reductive.”
Although Gaga defended herself against those accusations, she has yet to comment on Madge's most recent jab.
Time to choose sides, which icon are you siding with?